Fluoride Toxicity

Melatonin Protection on Mercury Exerted Brain Toxicity in the Rat. Mandava V. Rao, Anshita Purohit Zoology Department, University School of Sciences, Gujarat University, Ahmedabad 380 009, India. Website: www.zoologygujaratuni.org Abstract: Effect of melatonin on the neuro nephrotoxicity express on by mercuric chloride was studied. Adult rats were fed orally with ii different doses of mercuric chloride (2mg; 4mg/kg body weight) to survey thought toxicity with respect to cerebral cerebral hemisphere, cerebellum, myeline oblongata regions for 60 eld with and without supplementation of melatonin (5mg/kg body weight) intraperitoneally. The results signify that the graded doses of mercury elicit the depletion of the enzymatic activities like adenosine triphosphatase, succinate dehydrogenase, phosphorylase, saltlike phosphatase, acid phosphatase, and neutered glycogen, protein and lipid peroxidation levels in creative brain of cerebral hemisphere, cerebellum and me dulla oblongata of brain affecting their respective functions. root glucose and mercury levels increased followed by a reduction in body and organ weights. on the whole these effects seemed to be severe in cerebral hemisphere of brain.

Further bear on indices were to some extent maintained in the brain of animals co-treated with melatonin cover it protective role against mercury exerted neurotoxicity in the rat brain. entering: Mercury is a serious environmental and occupational pollutant with toxic effects in all the liveliness organisms (Berlin, 1987). Primary exposures results due(p) to environmental contamination caused as a re sult of mining, smelting, protracted industr! ial and agricultural usage including stirring and ingestion via the feed chain. It enters in the body in contour of chemical forms that ar elemental, inorganic and organic, exhibiting its toxicology characters including neurotoxicity, nephrotoxicity, reproductive toxicity and GI toxicity with ulcer and hemorrhage (Clausen, 1993; Hua et...If you want to observe a sufficient essay, order it on our website: BestEssayCheap.com

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